Enteric and Respiratory Enteroviruses Dashboard

This dashboard contains companion data for our manuscript:

Comparison of tissue tropism and host response to enteric and respiratory enteroviruses.
Ines Cordeiro Filipe, Han Kang Tee, Julien Prados, Isabelle Piuz, Samuel Constant, Song Huang and Caroline Tapparel.
Access abstract and full text [here]

Using the dashbord menu on the left, you will be able to interactively browse the data of the RNA-seq experiments we performed.

Gene Selection

Barplot

Legend

The above barplots display raw gene expression level of the selected genes in all the sample. Each condition is done in duplicate and expression level of indivual samples is shown by points while the bars end at the average expression level. Genes expression levels are expressed in Read Per Million.

Scatter plot

Legend

The above scatterplot display the average expression level of all the genes for the selected conditions. Genes expression levels are expressed in Read Per Million. Note that the axis are log-scaled, so the distance to the diagonal is proportional to the log-fold-change between the selected conditions.

Reactome.org

Legend

The above figure shows all genes associated with the main Reactome.org categories (a gene can appear several time if it belong to multiple categories). The gene color reflects its fold-change between the infected tissue and the corresponding Mock condition (for the selected tissue and virus). Using control on the left, user can adapt the colorpalette used, the color saturation, the point sizes, and the display of the labels.

Data download

Raw and processed data are available to download on NCBI GEO (accession number GSE184488 )

Tapparel Lab

Faculty of Medicine
University of Geneva, Switzerland
https://www.unige.ch/medecine/mimo/...
caroline.tapparel@unige.ch

Bioinformatics Support Platform

Faculty of Medicine
University of Geneva, Switzerland
https://www.unige.ch/medecine/bioinformatics
julien.prados@unige.ch